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Prevalence and factors associated with intestinal schistosomiasis and human fascioliasis among school children in Amhara Regional State, Ethiopia

Bekana, Teshome; etal (2023-04-06)

Background: Schistosomiasis and fascioliasis are digenean parasitic infections and are among the neglected tropical diseases that have both medical and veterinary importance. They are found mainly in areas having ...

Travel to farms in the lowlands and inadequate malaria information significantly predict malaria in villages around Lake Tana, northwest Ethiopia: a matched case–control study

Malede1, Asmamaw; etal (2023-04-06)

: In Ethiopia, malaria has declined in the last decade; only a small number of cases have been reported, primarily from hotspots. The contribution of house proximity to water bodies and the role of migration in ...

Efficacy of a single dose versus a multiple dose regimen of Mebendazole against hookworm infections among school children: a randomized open-label trial

Eshetu, Tegegne; etal (2023-04-06)

Background: Despite the existence of a population-based control program using single dose albendazole or mebendazole as a preventive chemotherapy, hookworm transmission remains high. It causes a negative impact on the ...

Prevalence of intestinal helminth infection among school children in Maksegnit and Enfranz Towns, northwestern Ethiopia, with emphasis on Schistosoma mansoni infection

Gashaw1, Fikru; etal (2023-04-06)

Background: Schistosomiasis is endemic in Ethiopia and previously unknown transmission foci have been reported from time to time in different parts of the country. Further surveys are required in areas where endemicity ...

Barriers of persistent long-lasting insecticidal nets utilization in villages around Lake Tana, Northwest Ethiopia: a qualitative study

Malede, Asmamaw; etal (2023-04-06)

Background: Malaria remains a major public health problem in Ethiopia. The use of LLINs is an effective approach to reducing transmission. Persistent use of LLINs is determined by numerous factors. Quantitative studies ...

In vivo and in vitro efficacy of a single dose of albendazole against hookworm infection in northwest Ethiopia: open-label trial

Bezie, Wolelaw; etal (2023-04-06)

Background: Control of hookworm and other soil-transmitted helminth infections primarily relies on preventive chemotherapy using a single dose of albendazole/mebendazole drugs on high-risk groups. Herein, the efficacy of ...

HBsAg Prevalence and Determinant Risk Factors among Voluntary Counseling and Testing Clients Visiting Gondar Health Center, Northwest Ethiopia

Ashebir1, Yitayew; etal (2023-04-06)

lobally, an astounding number of people are infected with HBV, HCV and HIV. Due to shared routes of transmission, HBV and human immunodeficiency virus co-infection is common and is an emerging concern in the clinical ...

Plasmodium falciparum histidine-rich protein 2 and 3 genes deletion in global settings (2010– 2021): a systematic review and meta-analysis

Jejaw Zeleke, Ayalew; etal (2023-04-06)

ackground: The usefulness of histidine-rich protein-2/3 (HRP2/3)-based rapid diagnostic tests of malaria due to Plasmodium falciparum has been threatened by the appearance of mutant PfHRP2/3 genes. This study was undertaken ...

Prevalence and Reinfection Rates of Schistosoma mansoni and Praziquantel Efficacy against the Parasite among Primary School Children in Sanja Town, Northwest Ethiopia

Woldegerima, Eden; etal (2023-04-06)

Background. Schistosomiasis is among the most widespread chronic infections in the world. The magnitude of the infection may show variations across different areas with respect to time. Praziquantel is a first line drug ...

Hematological and Biochemical Profile of Patients Infected with Schistosoma mansoni in Comparison with Apparently Healthy Individuals at Sanja Town, Northwest Ethiopia: A CrossSectional Study

Dessie, Nega; etal (2023-04-06)

ackground. Schistosomiasis is a parasitic disease that resides in the vascular system of vertebrates, causing a chronic, debilitating disease that affects more than 200 million people and 800,000 deaths per year in over ...

Liver Enzymes and Lipid Profile of Malaria Patients Before and After Antimalarial Drug Treatment at Dembia Primary Hospital and Teda Health Center, Northwest, Ethiopia

Megabiaw, Fentahun; etal (2023-04-06)

nfection with malaria in humans involves liver cell destruction, which alters the levels of liver enzymes and lipid profiles. A number of studies have been conducted to address the impact of malaria on liver enzymes and ...

TUMOR NECROSIS FACTOR ALPHA-308 GENE POLYMORPHISM AND RISK OF PLASMODIUM FALCIPARUM MALARIA AMONG PEOPLE LIVING IN DEMBIA WOREDA, NORTH WEST ETHIOPIA

Tegenaw, Kibrenesh; etal (2023-04-06)

Plasmodium falciparum is the most dangerous species of Plasmodium parasites in terms of lethality and morbidity. In different studies, polymorphisms in the tumor necrosis factor alpha (TNF-α) gene have been associated ...

Prevalence of HIV and Its Co-Infection with Hepatitis B/C Virus Among Chronic Liver Disease Patients in Ethiopia

Tassachew, Yayehyirad; etal (2023-05-30)

Background: The efficient use of antiretroviral drugs has significantly reduced AIDS-related morbidities and mortalities; however, mortality due to non-AIDS-related end-stage liver diseases is escalating in those living ...

Molecular epidemiology of hepatitis B virus among HIV co-infected and mono-infected cohorts in Northwest Ethiopia

Belyhun, Yeshambel; etal (2023-05-30)

Background: Hepatitis B virus (HBV) infection is a particular concern in human immunodeficiency virus (HIV) infected individuals. In Ethiopia, detailed clinical and virological descriptions of HBV prevailing during HIV ...

Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia

Belyhun, Yeshambel; etal (2023-05-30)

Among the major mutant variants detected, double BCP mutations (A1762T/G1764A) (25.9%), Kozak sequences mutations (nt1809-1812) (51.7%) and the classical PC mutations such as A1814C/C1816T (15.4%), G1896A (25.2%) and ...

Clade homogeneity and low rate of delta virus despite hyperendemicity of hepatitis B virus in Ethiopia

Belyhun1, Yeshambel; etal (2023-05-30)

Background: Although hepatitis B virus (HBV) is hyperendemic and heterogeneous in its genetic diversity in Ethiopia, little is known about hepatitis D virus (HDV) circulating genotypes and molecular diversity. Methods: ...

Hepatitis viruses in Ethiopia: a systematic review and meta-analysis

Belyhun1, Yeshambel2*; etal (2023-05-30)

Background: The existing seroepidemiological data on viral hepatitis in Ethiopia showed a wide variation in prevalence pattern and the clinical and public health burden have been underestimated. The aim of this ...

Ocular bacterial infections and antibiotic resistance patterns in patients attending Gondar Teaching Hospital, Northwest Ethiopia

Belyhun, Yeshambel; etal (2023-05-30)

Objectives: Empirical selections of antimicrobial therapy based on clinical observations are common clinical practices in Ethiopia. This study identified common external ocular infections and determined antibiotic ...

Clade homogeneity and low rate of delta virus despite hyperendemicity of hepatitis B virus in Ethiopia

Belyhun1, Yeshambel; etal (2023-05-30)

HDV, Genotype, Clade homogeneity, Ethiopia

Genital Chlamydia trachomatis Infection among Women of Reproductive Age Attending the Gynecology Clinic of Hawassa University Referral Hospital, Southern Ethiopia

Tadesse, Endale (2016)

Background Urogenital infection with Chlamydia trachomatis(CT) is one of the most common bacterial sexually transmitted infections (STIs) world-wide, especially in developing nations where routine laboratory diagnosis ...

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