Abstract:
Background: Protein-energy wasting is a major issue in patients with chronic kidney disease (CKD), adversely affecting functional activity, quality of life, morbidity and mortality. Assessment of nutritional status of individuals with chronic Kidney Disease (CKD) is important to ensure individual’s normal protein stores and avoid metabolic complications. However, in Ethiopia, there were very few studies done to assess the prevalence of protein-energy malnutrition and its associated factors among CKD patients. Therefore, the aim of this study was be to assess the association of protein energy malnutrition with chronic kidney disease (CKD) and its associated factors.
Objective: - To assess protein-energy wasting and associated factors among adult patients with chronic kidney disease in adult OPD in Northwest Amhara referral hospitals, Ethiopia 2024.
Methods
An institution based cross-sectional study was conducted from Jun 01/2024 to July 30/2024 in northwest Amhara national regional state referral hospitals. Data were collected using a structured interviewer-administered questionnaire and anthropometric measurements, and laboratory data was collected from patient files using checklist. Data was entered into Epi-data version 3.1 and analyze using SPSS version 27. Binary logistic regression analyses were performed to identify associated factors. P values <0.05 were considered to declare statistical significance.
Result: In this study, 806 study participants were interviewed the response rate of 95.72%. The study revealed that the prevalence of protein-energy wasting among CKD patients was 37.10%, in the multivariable analysis age, duration of CKD, and stage of CKD were found to be statistically significant factors influencing the likelihood of protein-energy wasting.
Conclusion: Protein-energy wasting was highly prevalent in CKD patients and was correlated with age, duration of CKD, and stage of CKD. Medical treatment for people with chronic kidney disease (CKD) must be combined with lifestyle modifications and nutritional interventions.
