Chronic Kidney Disease and Associated Factors among Highly Active Antiretroviral Therapy Naïve and Experienced HIV Infected Individuals at the University of Gondar Hospital, Gondar, Northwest Ethiopia.

Abstract

Background: Chronic kidney disease has emerged as one of the primary co-morbid conditions affecting human immunodeficiency virus infected individuals even after highly-active antiretroviral therapy. Objectives: To assess chronic kidney disease and associated factors among highly active antiretroviral therapy naïve and experienced HIV infected individuals at the University of Gondar Hospital, Gondar, Northwest Ethiopia. Method: A Hospital based comparative cross-sectional study was carried out at the University of Gondar Hospital from March to May, 2017. Double population proportion formula and convenient sampling technique were used to select 250 study participants. Socio-demographic and clinical data were collected by using pretested semi-structured questionnaire. The collected data were entered into Epi-Info version 3.5.1 and analyzed using SPSS version 20. Descriptive statistics, independent t-test, bivariable and multivariable logistic regression analysis were performed. A p-value of <0.05 was considered as statistically significant.