Abstract:
Abstract
Background: Traumatic brain injury in pediatrics is one of the commonest causes of morbidity,
disability and mortality worldwide. In low- and middle-income countries Study showed that death
of pediatrics from traumatic brain injury was 7.3%. However, there is limited data towards the
outcome of traumatic brain injury and its associated factors in Ethiopia.
Objective: To assess the outcome of traumatic brain injury and associated factors among
pediatrics patients in Amhara National Regional State Comprehensive Specialized Hospitals,
Ethiopia.
Methods: An institution based retrospective cross-sectional study was conducted among 423
pediatrics patients from January 1, 2019 to December 30, 2021, and data extraction period was
from May 16 to June15, 2022. Systematic random sampling technique was employed to select the
study participants. Data were collected from patient charts and registry books by using a data
extraction tool. Data were entered into the Epi-info version 7 and analysis was done by using SPSS
Version 25. Both Bi-variable and multi-variable analyses were employed to identify factors
associated with outcome of traumatic brain injury.
Result: From 423 sampled study participant charts 404 of them had complete information with
response rate of 95.5% and included in the final analysis. The overall unfavorable outcome of
traumatic brain injury at discharge was found that 12.13% (95% CI: 9.1% - 15.7 %). Sever
traumatic brain injury [AOR: 5.11(CI :1.8-14.48)], moderate traumatic brain injury
[AOR:2.44(CI:1.07-5.58)], Hyperglycemia [AOR: 3.01 (CI:1.1-8.04)], sign of increased
intracranial pressure [AOR:7.4(CI:3.5-15.26)], and medical comorbidity [AOR: 2.65(CI:1.19-
5.91)] were predicted of unfavorable outcome of traumatic brain injury pediatrics patient.
Conclusion and recommendations: Near about one in ten of traumatic brain injury results
unfavorable outcome. Sever and moderate form of traumatic brain injury, hyperglycemia, signs of
increased intracranial pressure, and medical comorbidity were factors associated with unfavorable
outcome of traumatic brain injury in children. Therefore, it is preferable to improve accesses to
acute and post-acute care services to lower the unfavorable outcome of traumatic brain injury in
childre
