Abstract:
Abstract
Introduction: Emergence agitation is one of the significant post-anesthetic and surgery
related complication which could occur during the recovery period and had a deleterious
effect if it occurred.
Objective: This study was aimed to assess incidence and factors associated of emergence
agitation after general anesthesia in pediatric patients at University of Gondar
comprehensive specialized Hospital.
Methods: A prospective follow up study was conducted to assess the incidence and
identify contributing factors of emergence agitation among 153 pediatric patients aged 2-9
years who were operated under general anesthesia at University of Gondar comprehensive
specialized Hospital operation rooms from first February to April 30, 2019. Emergence
agitation was recorded by pediatrics anesthesia emergence delirium scale and the other
variables were collected by a questionnaire. The data was analyzed using SPSS version 20
software. Descriptive statistics conducted to summarize patient’s information and to
determine the incidence. To identify associated factors binary logistic regression was held,
and a p-value <0.05 was considered as significant.
Results: Emergence agitation was experienced on eighty (52.3%) children with a mean
and standard deviation of 12±5.9 minutes of duration. Among agitated children, 8(10%) of
them developed adverse events related to agitation. From multi-variable analysis difficult
parental separation behavior (AOR =2.688, 95% CI=1.131-6.39), children aged 2-5 years
(AOR =2.688, 95% CI=1.131-6.3925), isoflurane maintenance (AOR=4.001, 95%
CI=1.733-9.234) and propofol administration after maintenance closure (AOR=0.145, 95%
CI=0.030-0.695) were significantly associated with agitation.
Conclusion and recommendations: The factors associated to cause emergence agitation were
being preschool child, difficulty parental separation, and isoflurane maintenance. But propofol
administration after maintenance closure found to be protective. We strongly recommend that
agitation should be assessed and detected in the postoperative period, preventive measures
should be taken to decrease the incidence, efforts should apply to calm and cooperate the
pediatric patients who will be ready to have surgery.
Key Words: Emergence agitation, incidence, associated factors, general anesthesi
