Evaluation of In Vivo Antiulcer Activity of Hydro-Methanol Extract and Solvent Fractions of the Stem Bark of Ficus thonningii (Moraceae) on Rodent Models

Abstract

Peptic ulcer disease (PUD) is a destruction in a part of the gastrointestinal mucosa that may pass through the muscularis mucosa. Depending on the site of ulcer, PUD can be gastric ulcer (stomach) or duodenal ulcer (duodenum) [1]. PUD is the most common gastrointestinal disease with a worldwide prevalence of about 40% in developed and 80% in developing countries