TUBERCULOSIS INFECTION AMONG ADULT HIV PATIENTS ATTENDING ANTIRETROVIRAL THERAPY CLINIC AT UNIVERSITY OF GONDAR REFERRAL HOSPITAL OF ETHIOPIA

Abstract

Despite increased deliverance of antiretroviral therapy, morbidity and mortality from TB are still predominant among HIV/AIDS infected patients in Ethiopia. Thus, the current study aimed to determine incidence and predictors of tuberculosis among HIV infected patients at university of Gondar referral specialized teaching hospital, Ethiopia, 2018. Institutional based retrospective follow-up study was conducted among study population which was HIV infected individuals registered from September 2013 to September, 2018. The data were collected using structured data extraction form. The data were checked for completeness, cleanness and entered into Epi Info 7.0 and analyzed using SPSS version (IBM-23). Statistical significance was inferred at P-value ≤ 0.05. Adjusted odd ratio (AOR) with 95% confidence interval (CI) was used to determine predictors. Among 494 patients’ charts were abstracted 275 (55.7%) and new TB cases were found. Cumulative and incidence density of tuberculosis was 6.875% and 55 per 100 person year respectively. Divorced Marital status, family size, tobacco user behavioral factors baseline, WHO clinical stage IV,CD4 count at present, CD4 count at diagnosis <200, drug adherence and hematocrit count, were important determinant/risk factors of tuberculosis among HIV infected patients. Relatively high tuberculosis cases were established among HIV infected patients.