Abstract:
Objectives: This study aims to determine bacterial profile and antimicrobial susceptibility patterns of chronic suppurative
otitis media in the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.
Result: Sixty-two ear swabs were collected and 74 bacterial isolates were identified, of which 48 (77.4%) sample
with mono-microbial growth, 11 (17.8%) with polymicrobial growth and the remaining 3 (4.8%) show no growth. The
most common isolates were Proteus mirabilis 16 (21.6%), followed by S. aureus 12 (16.2%), Klebsiella spp. 10 (13.5%) and
Providencia spp. 11 (14.9%). Proteus mirabilis was 100% susceptible to norfloxacin and ciprofloxacin while 87.5% of the
isolates were susceptible to cefixime and gentamicin. S. aureus was 83.3% susceptible to gentamicin and clarithromycin,
while 75% of the isolates were susceptible to amoxicillin–clavulanic acid and chloramphenicol, however, 66.7%
the isolates were susceptible to ciprofloxacin, norfloxacin and erythromycin. The overall prevalence of multidrug
resistance in the current study was 35 (47.3%). In this study P. mirabilis, S. aureus, Providencia spp., and Klebsiella spp.
were the most common bacterial isolate and all Gram negative isolates were susceptible to ciprofloxacin and norfloxacin.
Amoxicillin–clavulanic acid, gentamicin, chloramphenicol, clarithromycin and tobramycin were relatively
effective against Gram positive bacteria
