Abstract:
Objective: Cognitive impairments are now widely recognized and emerging as an important therapeutic target in
a patient with a major depressive disorder (MDD). It associated with a more deteriorating course of illness among
MDD patients. Therefore, understanding the level of cognitive impairment and associated factors is crucial to provide
optimal care for MDD patients.
Result: The proportion of cognitive impairment among MDD patients was found to be 54.4% (95%, CI (49.6, 59.3).
Factors significantly associated with having cognitive impairment were age adjusted odds ratio (AOR) = 3.00,
95%, confidence interval (CI): (1.49, 6.03), educational status, (AOR = 5.36, 95% CI 2.16, 13.26), employment status
(AOR = 3.63, 95 CI 1.99, 6.62), duration of the illness (AOR = 3.16, 95% CI 1.31, 7.64), having co-morbid psychiatric illnesses
(AOR = 2.16, 95% CI 1.26, 3.71), and illness relapse (AOR = 2.97, 95% CI 1.54, 5.73).
