Abstract:
Depression is a substantial contributor to the global burden of disease and affects people in all communities across the
globe. Depression is the most common psychiatric problem associated with HIV/AIDS and half of all PLWHIV with depression
go underdiagnosed and untreated. Psychiatric complications of HIVAIDS delay mental health services in less affluent countries.
However,thereislackofstudywithregardtothepooledestimationprevalenceofdepressioninPLWHIVinEthiopia.
Objectives
.The
aimofthissystematicreviewandmeta-analysisistosummarizethemostcurrentavailableevidencefrom2010toMarch2017among
adult PLWHIV in Ethiopia.
Methods
. The team explored multiple databases searching methods including MEDLINE/PubMed,
PsycINFO, Google Advance Scholar, and Google Scholar to find studies published with the data on the prevalence of depression
among PLWHIV. We searched 150 research articles; of these 143 articles were excluded. Subsequently, thirteen articles were used
for synthesis prevalence and four studies were included in the synthesis effect of sex on depression among PLWHIV.
Results
.The
total of pooled estimated prevalence of depression in PLWHIV was 36.65. Estimated prevalence of depression in three studies by
using CES-D was 31.19% and in six studies by using PHQ-9 was 37.91%. The remaining four studies used a single tool: Kessler-6
Scale (15.5%), HADS (41.2%), HDSQ (43.9%), and BDI (55.8%). Factors such as age, marital status, living alone, poor medication
adherence, poor social support, clinical stages II and III of HIV, st
igma, income, and occupation were significantly associated with
depression.
Conclusions and Recommendation
. The pooled estimate prevalence of depression among PLWHIV was higher than that
in the general population. It is better to offer special attention to these populations