Abstract:
Glaucoma is a chronic disease characterized by irreversible optic nerve damage and visual field loss
that leads to visual impairment and blindness; ultimately limiting personal independence and compromising overall
quality of life of affected individuals. There is paucity of information on how glaucoma affects the quality of life of
patients in low and middle-income countries where resources for both diagnosis and treatment of such conditions
are limited. In this study we investigate the impact of glaucoma on quality of life in Ethiopian patients.
Methods: The quality of life of 307 glaucoma patients and 76 normal controls that were frequency matched to the
age and sex profiles of the cases was assessed using Amharic version of Glaucoma Quality of Life −15 questionnaire.
Linear regression models and the t-test were employed to compare significant differences in GQL-15 scores and to
generate mean and mean differences between cases and controls respectively.
Results: The mean GQL-15 score in the glaucoma cases was substantially higher (indicating poorer quality of life) than
the controls [cases 46.3 (95% CI, 28.8–63.8) and controls 18.6 (95% CI, 15.2–22.0), p < 0.0001]. Cases with normal visual
acuity and mild glaucoma had significantly higher scores than the controls. Poorer quality of life was associated with
age ≥ 71 years old 51.1 (95%CI, 26.2–75.9), rural residence 55.7 (95%CI, 49.9–61.5), monthly income of <400 Birr (53.1;
95%CI, 50.5–55.6), diagnosis time 1–5 years (49.6; 95%CI, 41.2–57.9), severe visual impairment (70.5; 95%CI, 58.1–82.8),
and advanced glaucoma (50.9; 95%CI, 43.6–58.3).
Conclusion: These glaucoma patients, including those with normal visual acuity and early disease, had poorer quality
of life compared to normal controls. Older age, rural residence, low income and more advanced disease were significantly
associated with poorer quality of life. There is a need to increase awareness of the impact of glaucoma among clinicians,
patients and their families, for a better understanding of the impact this disease has on a person’slife.
